Brian Joseph Brohm (born September 23, 1985) is an American football coach and former quarterback who is the offensive coordinator and quarterbacks coach at the University of Louisville. He played professionally in the National Football League (NFL) and Canadian Football League (CFL).

Brohm played college football for Louisville and was selected by the Green Bay Packers in the second round of the 2008 NFL draft. He also played in the NFL for the Buffalo Bills and the CFL's Hamilton Tiger-Cats and Winnipeg Blue Bombers, as well as the Las Vegas Locomotives of the United Football League

While passing for 10,579 yards and 119 touchdowns during his prep career, Brohm led the Trinity Shamrocks to the 4-A state title in 2001, 2002, and 2003. He was the MVP of all three title games, the most exciting of which was a 59–56 victory over Louisville Male High School and 2002 Mr. Football Michael Bush. Brohm threw for 552 yards and 7 TDs in that game. Brian was featured on the cover of Sports Illustrated on November 18, 2002, while he was a junior in high school.

Brohm was named 2003 Kentucky Mr. Football, USA Today Offensive Player of the Year and was the Kentucky Gatorade Player of the Year for 2003. Brohm was named one of the top five quarterbacks in America by Rivals.com and was selected to participate in the 2004 U.S. Army All-American Bowl game in San Antonio, Texas.

Brohm played basketball and baseball for the Shamrocks, helping the basketball team to its first ever Regional title and the baseball team to a state runner-up finish. He was the MVP of the only State tournament victory in Trinity history, when they defeated University Heights Academy in 2004. Brohm was also voted the MVP of his baseball team his senior year. Following his senior year he was drafted by the Colorado Rockies in the 49th round of the 2004 MLB draft.

Brohm announced his decision to attend the University of Louisville on January 20, 2004, picking the hometown Cardinals over scholarship offers from Notre Dame, Tennessee and Alabama, among others. Brohm enrolled at Louisville in the fall of 2004 and immediately began competing for the starting quarterback spot with Stefan LeFors.

In his first season, Brohm was named Conference USA Freshman of the Year, despite not starting a single game, but he helped lead the Cardinals to the 2004 Liberty Bowl against Boise State and a #6 ranking to end the season. Brohm completed 66 of 98 passes for 819 yards and six touchdowns. After entering the game for at least one series per game as a true freshman, Brohm followed in the footsteps of father, Oscar, and brother, Jeff, by becoming a starting quarterback at the University of Louisville in 2005. His brother, Greg, also played at Louisville as a receiver.

In 2005, Brohm passed for 2,883 yards and 19 touchdowns before sustaining a season-ending knee injury in a game against Syracuse on November 25. He was forced to miss Louisville's last regular season game (a December 2 matchup against (Connecticut) and was still in rehabilitation when the Cardinals lost to Virginia Tech in the 2006 Gator Bowl. Brohm was named the Big East Offensive Player of the Year and 1st Team All-Big East Quarterback in 2005.