Brianna Wu is married to Frank Wu. He is a consistent supporter and partner.

The Gamergate controversy significantly impacted Wu's personal life, causing severe stress and requiring her and her husband to flee their home due to death threats. This period reflects the extreme challenges faced due to online harassment.

Frank Wu's unwavering support has been a constant throughout the challenges posed by Gamergate and Brianna's public profile. Their strong relationship is a notable aspect of her personal life.