Buffy the Vampire Slayer Season Ten is the sequel to the Season Nine comic book series, a canonical continuation of the television series Buffy the Vampire Slayer. The series is published by Dark Horse Comics and ran from March 2014 to August 2016.

The Season Ten brand continues the two ongoing component series that formed Season Nine: Buffy and Angel & Faith. The creative team of Angel & Faith in Season Nine, writer Christos Gage and penciler Rebekah Isaacs, are the creative team behind Buffy Season Ten. Victor Gischler and Will Conrad took over Angel & Faith in this season. Unlike with Season Nine, there were no spin-off series in addition to the two core series. There was however a short story titled "Where Are They Now", published in Dark Horse Day Sampler 2016.

The series was followed by Season Eleven which began November 23, 2016.

As in the preparation for the previous season, there was a writer's summit in spring 2013, months before Season Nine ended. Along with all the creators from Season Nine, Victor Gischler and Buffy the Vampire Slayer actor Nicholas Brendon joined the team.

Buffy and her friends must quickly get to grips with the new rules of magic created at the end of Season Nine when they encounter a new breed of vampires which can shapeshift, walk in sunlight, and which is generally harder to kill. Another consequence is that Buffy's sister Dawn, though alive again thanks to the recreation of magic, has had a traumatic time adjusting to life; she feels her mother's death as if the event was recent, and her feelings for her boyfriend Xander have reset as well. Meanwhile, Xander is secretly haunted by apparitions of his dead ex-fiance Anya; he does not know if she is real or a hallucination. However, all is not bleak, as Buffy's old mentor Giles is delivered to her by Faith alive and mentally intact, but in the body of a child, following the events of Angel & Faith in the previous season. The group soon learn that the now-blank Vampyr book given to Buffy back in 1997 can be used to write new rules for magic, and quickly realizing what a danger this book is, the gang forms an alliance with the demon D'Hoffryn and other interested parties to keep the book safe and act as stewards over the new and unstable rules of magic. They consider the needs of various mystical groups willing to make peace with humans including a mutually non-lethal agreement with the majority of the world's vampires, led by Harmony Kendall.

The gang does some growing up. Willow prevents Andrew from making a terrible mistake with the Vampyr book when he attempts to resurrect her long-dead girlfriend Tara, whose death he feels responsible for, and confronts his tendency to act impulsively – sometimes with good motivations – but without regard for other people's consent or feelings. He does however activate a digital recording of the personality of his friend and victim Jonathan Levinson. Some time later, after some soul searching, Andrew realizes he is gay. Meanwhile, Willow, ends her relationship with the demon witch Aluwyn, having grown apart, and Xander and Dawn decide to take things slow. Buffy and Spike confront the fact that they've grown closer to each other, and Buffy realizes she loves Spike, and they become a couple. Buffy stands by Spike when it appears that an evil outside force is controlling him at night, and they soon track this force down: an ancient vampire named Archaeus who is part of the same lineage as Spike and Angel, Archaeus having directly sired the Master. Temporarily getting away from the powerful demon, the group realize they will have to bring Angel in on the development. Buffy is able to put the events of Season Eight, in which Angel was influenced by a higher power into being a villain, behind her, but there is initial awkwardness in the group as they attempt to confront Archaeus. However, working together, Buffy, Angel and Spike are able to wound Archaeus and kill his servants with the Scythe, so Archaeus flees. D'Hoffryn informs Buffy that a portal Archaeus was using, which opens into hell dimensions, is called the Restless Door and is being repaired by an alliance of enemies faced by the gang this season: the Old One, the Soul Glutton; the siren, Mistress; and the flesh demon, the Sculptor, who wish to overrun Earth with demons. Angel leaves to warn his friends in London, giving Spike his blessing and accepting a place as a friend in Buffy's life, but confides in Willow that he believes Spike's self-destructiveness will doom his relationship with Buffy.

When Buffy's father Hank announces he doesn't want Buffy to be a part of his wedding due to her being a Slayer, she finds herself surprisingly hurt by this. On a different mission, a demon triggers Buffy's memories of her attempted rape by a soulless Spike. She explains to Spike that she doesn't blame him for his actions when he didn't have a soul, but that she will always remember them, and that he has to respect that she will always have to deal with them in her own way. Meanwhile, Anya's ghost transpires to be the puppet of an unseen force and completely unaware that she is not Anya; it is exploiting Xander as a weak link in Buffy's circle. Later, demon invasions caused by the Restless Door become a global threat. The Slayer Satsu, who once had a fling with Buffy, attempts to convince Buffy that she needs to work with the military as they are the only ones with the resources to help and since she forgave Angel, the military also deserves another chance. The military needs Buffy and Spike to recruit both types of vampires to help battle the demon invasions. The vampires are represented by Harmony and Vicki who have Buffy and Spike win trials of combat to gain the vampires alliance. The two vampire leaders also point out the insecurities in Buffy's and Spike's relationship. Spike later meets with a woman from his past, Dylan, first seen in the Spike: Into the Light (2014) comic. Dylan thanks Spike for giving her the courage to grow as a person and wants a friendship with both him and Buffy. Meanwhile, Buffy is outraged at Willow's eagerness to work for the military, helping them understand magic. Willow believes this is right and has an attraction to Lake Stevens, a woman who leads the military's supernatural unit. Willow and Buffy acknowledge they are changing but agree to not let this disagreement divide them.

To help battle the invasions Buffy reluctantly agrees to use the Vampyr book to increase the powers of D'Hoffryn's Demon Council with the limit that the powers are for the one in office, not the demon themselves. Giles grows close to the Fae folk who accept him in both mind and body, though his favoritism of them leads to some tension with Buffy. The Sculptor offers to make Andrew a human body for Jonathan's digital personality if Andrew steals the Scythe. Andrew tricks the Sculptor into thinking he complied but he actually told Buffy beforehand and she kills the Sculptor. Realising his new body will disintegrate, Jonathan runs off, furious at Andrew betraying him again. Though Andrew is hurt, he has stopped living out his fantasies and is ready to face the real world with the Scoobies. Xander admits to Ghost Anya he knows she isn't actually Anya and decides to ignore her. The Scoobies find and overwhelm the Siren Mistress and Soul Glutton, to escape, the two destroy the Restless Door; creating an unstable portal that will consume Earth unless Dawn as The Key can close it. Being in a magical dimension gives Dawn great power but she can only close the portal from the demon's side and will be stuck there if she does. To save Earth she agrees and convinces the others this is the right choice and they promise to find another way to bring her home. Xander stays with Dawn, leaving Ghost Anya alone and vengeful on Earth. As the Scoobies leave, Buffy wishes D'Hoffryn's Council could just kill the Soul Glutton and Siren Mistress without their help. Ghost Anya secretly grants this wish. After killing the two, D'Hoffryn tells Ghost Anya she was a copy he made and now that she has activated her vengeance powers she becomes corporeal. D'Hoffryn is now ready to take the Vampyr book to give himself power.