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Bunitrolol
Bunitrolol is a beta-adrenergic antagonist.
2-Hydroxybenzonitrile (1) is treated with epichlorohydrin and sodium hydroxide to give the epoxide (2). Addition of tert-butylamine completes the synthesis of bunitrolol.
Bunitrolol
Bunitrolol is a beta-adrenergic antagonist.
2-Hydroxybenzonitrile (1) is treated with epichlorohydrin and sodium hydroxide to give the epoxide (2). Addition of tert-butylamine completes the synthesis of bunitrolol.
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