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Butaperazine
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Butaperazine
Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class. It was approved in 1967, and possibly discontinued in the 1980s.
Butaperazine can be synthesized starting from 2-butyrylphenothiazine (1). It is prepared in a manner that is comparable to the method used in the synthesis of propiomazine and propiopromazine.[clarification needed] The phenothiazine is alkylated with 1-(γ-chloropropyl)-4-methylpiperazine (2), which is prepared in the conventional way by alkylating 1-methylpiperazine with 1-bromo-3-chloropropane.
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Butaperazine
Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class. It was approved in 1967, and possibly discontinued in the 1980s.
Butaperazine can be synthesized starting from 2-butyrylphenothiazine (1). It is prepared in a manner that is comparable to the method used in the synthesis of propiomazine and propiopromazine.[clarification needed] The phenothiazine is alkylated with 1-(γ-chloropropyl)-4-methylpiperazine (2), which is prepared in the conventional way by alkylating 1-methylpiperazine with 1-bromo-3-chloropropane.
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