C. Natesa Mudaliar (1875–1937), also known as C. Natesan, was an Indian politician and activist of the Dravidian Movement from what became the Indian state of Tamil Nadu. He was one of the founders of the Justice Party, along with P. Theagaraya Chetty and T. M. Nair.

Mudaliar was born in Triplicane, Madras, in 1875. His early schooling was in Madras, following which he graduated from Presidency College and Madras Medical College before practising as a doctor.

Mudaliar founded the Madras United League in 1912 and was one of the founders of the South Indian Liberal Federation. He was elected to the Madras Legislative Council in 1923 as a candidate of the Justice Party and served as a legislator until 1937, when he died at the age of 62.

Natesa Mudaliar was born in Triplicane, Madras in 1875. He belongs to Thuluva Vellalar community. He had his early schooling in Madras and graduated in arts from the University of Madras. He worked as a lecturer in Pithapuram Maharaja College and as an interpreter in the Gordon Woodrof Company. He graduated in medicine from Madras Medical College and practiced as a doctor.

Natesa Mudaliar brought in two non-Brahmin priests from Coimbatore and celebrated his daughter's marriage without Brahmin priests as part of the Justice Party's ideology to do house rituals without the Brahmin priests.

In 1912, the Madras United League was formed. Mudaliar was one of the founders of the league and served as its Secretary. The league was largely composed of government employees and concentrated on improving the literacy of non-Brahmins by conducting adult education classes. In November 1912, the Madras United League was renamed as the Madras Dravidian Association and Panaganti Ramarayaningar, later the Raja of Panagal was elected president.

In 1914, while still a medical student in Madras, Natesa Mudaliar established "The Dravidian Home," a hostel for non-Brahmin students. Mudaliar had discovered that caste restrictions prevented non-Brahmins from finding hostel lodging in Madras. In the 2 years that the Home was operational, Mudaliar founded the Dravidian Association with the aim of enhancing non-Brahmin political authority through "Dravidian Upliftment."

Through the mediatory efforts of Mudaliar, political opponents Theagaroya Chetty and T. M. Nair came together and resolved to put forth their efforts to form an organization representing the non-Brahmins of the Madras Presidency.^{[citation needed]}