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CaBIG
The cancer Biomedical Informatics Grid (caBIG) was a US government program to develop an open-source, open access information network called caGrid for secure data exchange on cancer research. The initiative was developed by the National Cancer Institute (part of the National Institutes of Health) and was maintained by the Center for Biomedical Informatics and Information Technology (CBIIT) and program managed by Booz Allen Hamilton. In 2011 a report on caBIG raised significant questions about effectiveness and oversight, and its budget and scope were significantly trimmed. In May 2012, the National Cancer Informatics Program (NCIP) was created as caBIG's successor program.
The National Cancer Institute (NCI) of the United States funded the cancer Biomedical Informatics Grid (caBIG) initiative in spring 2004, headed by Kenneth Buetow. Its goal was to connect US biomedical cancer researchers using technology known as grid computing. The program, led by the Center for Bioinformatics and Information Technology (CBIIT), began with a 3-year pilot phase. The pilot phase concluded in March 2007, and a trial was announced. Buetow promoted the program in 2008.
In addition to caGrid, the underlying infrastructure for data sharing among organizations, caBIG developed software tools, data sharing policies, and common standards and vocabularies to facilitate data sharing.
Software tools targeted:
caBIG sought to provide foundational technology for an approach to biomedicine it called a “learning healthcare system.” This relies on the rapid exchange of information among all sectors of research and care, so that researchers and clinicians are able to collaboratively review and accurately incorporate the latest findings into their work. The ultimate goal was to speed the biomedical research process. It was also promoted for what is often called Personalized Medicine. caBIG technology was used in adaptive clinical trials such as the Investigation of Serial studies to Predict Your Therapeutic Response with Imaging and molecular AnaLysis 2 (I-SPY2), which was designed to use biomarkers to determine the appropriate therapy for women with advanced breast cancer.
Health information technology (HIT) was promoted for management and secure exchange of medical information among researchers, health care providers, and consumers. HIT initiatives mentioning caBIG were: NCI and the American Society of Clinical Oncology initiated a collaboration to create an oncology-specific electronic health record system using caBIG standards for interoperability and that will enable oncologists to manage patient information in an electronic format that accurately captures the specific interventional issues unique to oncology. The Nationwide Health Information Network was an initiative to share patient clinical data across geographically disparate sources and create electronically linked national health information exchange. It might be somehow related.
A BIG Health Consortium was formed in 2008 to promote personalized medicine, but disbanded in 2012. In July 2009, caBIG announced a collaboration with the Dr. Susan Love Research Foundation to build an online cohort of women willing to participate in clinical trials. Called the Army of Women, it had a goal of one million in its database; by December 2009 the site was "launched", and about 30,000 women and men signed up by 2010.
The Cancer Genome Atlas aimed to characterize more than 10,000 tumors across at least 20 cancers by 2015. caBIG provided connectivity, data standards, and tools to collect, organize, share, and analyze the diverse research data in its database. Since 2007, NCI worked with UK National Cancer Research Institute (NCRI). The two organizations shared technologies for collaborative research and the secure exchange of research data using caGrid and the NCRI Oncology Information Exchange (ONIX) web portal announced in August 2009. ONIX shut down in March 2012. The Duke Cancer Institute used caBIG clinical trials tools in their collaboration with the Beijing Cancer Hospital of Peking University.
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CaBIG AI simulator
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CaBIG
The cancer Biomedical Informatics Grid (caBIG) was a US government program to develop an open-source, open access information network called caGrid for secure data exchange on cancer research. The initiative was developed by the National Cancer Institute (part of the National Institutes of Health) and was maintained by the Center for Biomedical Informatics and Information Technology (CBIIT) and program managed by Booz Allen Hamilton. In 2011 a report on caBIG raised significant questions about effectiveness and oversight, and its budget and scope were significantly trimmed. In May 2012, the National Cancer Informatics Program (NCIP) was created as caBIG's successor program.
The National Cancer Institute (NCI) of the United States funded the cancer Biomedical Informatics Grid (caBIG) initiative in spring 2004, headed by Kenneth Buetow. Its goal was to connect US biomedical cancer researchers using technology known as grid computing. The program, led by the Center for Bioinformatics and Information Technology (CBIIT), began with a 3-year pilot phase. The pilot phase concluded in March 2007, and a trial was announced. Buetow promoted the program in 2008.
In addition to caGrid, the underlying infrastructure for data sharing among organizations, caBIG developed software tools, data sharing policies, and common standards and vocabularies to facilitate data sharing.
Software tools targeted:
caBIG sought to provide foundational technology for an approach to biomedicine it called a “learning healthcare system.” This relies on the rapid exchange of information among all sectors of research and care, so that researchers and clinicians are able to collaboratively review and accurately incorporate the latest findings into their work. The ultimate goal was to speed the biomedical research process. It was also promoted for what is often called Personalized Medicine. caBIG technology was used in adaptive clinical trials such as the Investigation of Serial studies to Predict Your Therapeutic Response with Imaging and molecular AnaLysis 2 (I-SPY2), which was designed to use biomarkers to determine the appropriate therapy for women with advanced breast cancer.
Health information technology (HIT) was promoted for management and secure exchange of medical information among researchers, health care providers, and consumers. HIT initiatives mentioning caBIG were: NCI and the American Society of Clinical Oncology initiated a collaboration to create an oncology-specific electronic health record system using caBIG standards for interoperability and that will enable oncologists to manage patient information in an electronic format that accurately captures the specific interventional issues unique to oncology. The Nationwide Health Information Network was an initiative to share patient clinical data across geographically disparate sources and create electronically linked national health information exchange. It might be somehow related.
A BIG Health Consortium was formed in 2008 to promote personalized medicine, but disbanded in 2012. In July 2009, caBIG announced a collaboration with the Dr. Susan Love Research Foundation to build an online cohort of women willing to participate in clinical trials. Called the Army of Women, it had a goal of one million in its database; by December 2009 the site was "launched", and about 30,000 women and men signed up by 2010.
The Cancer Genome Atlas aimed to characterize more than 10,000 tumors across at least 20 cancers by 2015. caBIG provided connectivity, data standards, and tools to collect, organize, share, and analyze the diverse research data in its database. Since 2007, NCI worked with UK National Cancer Research Institute (NCRI). The two organizations shared technologies for collaborative research and the secure exchange of research data using caGrid and the NCRI Oncology Information Exchange (ONIX) web portal announced in August 2009. ONIX shut down in March 2012. The Duke Cancer Institute used caBIG clinical trials tools in their collaboration with the Beijing Cancer Hospital of Peking University.