Cadmium fluoride (CdF₂) is a mostly water-insoluble source of cadmium used in oxygen-sensitive applications, such as the production of metallic alloys.

Cadmium fluoride is prepared by the reaction of gaseous fluorine or hydrogen fluoride with cadmium metal or its salts, such as the chloride, oxide, or sulfate.

It may also be obtained by dissolving cadmium carbonate in 40% hydrofluoric acid solution, evaporating the solution and drying in a vacuum at 150 °C.

Another method of preparing it is to mix cadmium chloride and ammonium fluoride solutions, followed by crystallization. The insoluble cadmium fluoride is filtered from solution.

Cadmium fluoride has also been prepared by reacting fluorine with cadmium sulfide. This reaction happens very quickly and forms nearly pure fluoride at much lower temperatures than other reactions used.

The standard enthalpy has been found to be −167.39 kcal·mole⁻¹ and the Gibbs energy of formation has been found to be −155.4 kcal·mole⁻¹. The heat of sublimation was determined to be 76 kcal. mole⁻¹

In extremely low concentrations (ppm), this and other fluoride compounds are used in limited medical treatment protocols.^{[citation needed]}

Fluoride compounds also have significant uses in synthetic organic chemistry.