Calçoene River is a river of Amapá state in north-eastern Brazil.

In 1894, the river was at the heart of gold rush with there were 6,000 to 10,000 gold miners active in and around the river.

2°30′25″N 50°49′15″W / 2.50694°N 50.82083°W / 2.50694; -50.82083