Cape Town CBD (sometimes referred to as Cape Town Central City or City Centre) is the central business district of Cape Town, and the economic centre of the city.

The CBD sits beneath Table Mountain, and alongside the Port of Cape Town. The N1 freeway connects the CBD with communities to the east and north-east (the Northern Suburbs) (via the M5 and N7) while the N2 and M3 freeways link the CBD with communities to the south-east (the Southern Suburbs).

Being the economic centre of the city, the CBD houses the headquarters of many large South African and multinational corporations.

The CBD is home to numerous tourist attractions and local amenities. The area is also traveled through in order to get from the freeways into the V&A Waterfront, and to approach Table Mountain from the front.

Unlike many other CBDs in South African metropolitan areas, Cape Town CBD is considered clean and safe, and has been well-maintained in terms of infrastructure. Numerous public-private partnerships exist to keep the CBD a desirable place to be, including the Cape Town Partnership and Cape Town Central City Improvement District (CCID).

In recent years, billions of rands of foreign investment has flowed into Cape Town CBD, and numerous businesses have moved employees, and their headquarters, from other South African CBDs into Cape Town's. The CBD is also a major destination for tourists, and it had its busiest year for tourism to date in 2024.

Cape Town CBD is in the City Bowl region of the city, positioned between the Port of Cape Town and Table Mountain to the east and west, and between De Waterkant and Bo-Kaap in the north, and District Six to the south.

The CBD sits roughly between Buitengracht Street on its northern border, and Buitenkant Street on its southern end. Orange Street runs along the CBD's western side, forming a border between it and Gardens. To the CBD's west is Nelson Mandela Boulevard.