Charlene Lipsey (born July 16, 1991) is an American middle-distance runner who specializes in the 800 metres. She competed in the women's 800 metres at the 2017 World Championships in Athletics.

Charlene Lipsey signed with Adidas in 2013 and trained at LSU until Fall 2016.

Lipsey moved to train with Philadelphia based Juventus Running Club and coach Derek Thompson.

Track star Charlene Lipsey received key to Hempstead Village in September 2017 from Mayor Don Ryan.

Charlene Lipsey was part of Team USA setting world indoor record in the February 3 at 2018 Millrose Games in 8:05.89 – Chrishuna Williams (2:05.10), Raevyn Rogers (2:00.45), Charlene Lipsey (2:01.98), Ajee' Wilson (1:58.37).

Charlene Lipsey won 2018 Sir Walter Miler in 4:27.28 in the same race Sara Vaughn, Cory McGee, Nicole Sifuentes, Kate Van Buskirk ran under 4:30.

For college, Lipsey chose to compete for the LSU Tigers track and field where she was an 8-Time All-American, Three-Time SEC Champion.

Lipsey graduated from Louisiana State University in 2013.