Chicago Tonight is a television news program broadcast weeknights on WTTW in Chicago, United States. It reports primarily on local politics, education, business, culture, science, and health, with a mix of in-studio panel discussions, one-on-one interviews, and short documentary-style packages. On its website, it publishes additional news stories and features by staff reporters.

The show first aired on April 24, 1984 and was hosted by popular Chicago broadcast journalist John Callaway for 15 years, who continued contributing to the show until he died in 2009.