Chisipite Senior School (or Chisipite) is an independent single-sex secondary day and boarding school for girls, located in Harare, Zimbabwe. The school is sited on 25 acres (10 ha) of land with 75+ academic staff and 750 girls (of whom 40 girls are boarders) enrolled.

Chisipite Senior School was ranked 67th out of the top 100 best high schools in Africa by Africa Almanac in 2003, based upon quality of education, student engagement, strength and activities of alumnae, school profile, internet and news visibility. Chisipite Senior was also ranked as one of the Top 10 High Schools in Zimbabwe in 2014.

Chisipite Senior School is a member of the Association of Trust Schools (ATS) and the Alliance of Girls' Schools Australasia; and the Head is a member of the Conference of Heads of Independent Schools in Zimbabwe (CHISZ).

Chisipite Senior School was opened in 1954 to cater for students who had finished their primary education at Chisipite Junior School. Initially, the school had two members of staff and 48 girls. Chisipite Senior School is "the first inter-denominational private girls school in Central Africa".

The name of the School, Chisipite, is derived from a spring rising in a nearby vlei. "Chisipiti" is the Shona word for spring. It has also inspired the fountain badge and the motto "Fons vitae caritas".

Chisipite Senior School has a house system consisting of 4 competitive houses which are Spring, St Paul, Patrons and Anderson. The houses compete in various sporting and cultural activities.

The following sporting disciplines are available at Chisipite: athletics, basketball, cross country, field hockey, indoor hockey, rowing, soccer, squash, swimming, tennis, volleyball and water polo.

The school's sport facilities include twelve tennis courts, two squash courts, three basketball, courts, three indoor hockey pitches, three volleyball courts, field facilities for up to four hockey and soccer fields and a swimming pool suitable for waterpolo and synchronized swimming.