Chris Eyre (born 1968), an enrolled citizen of the Cheyenne and Arapaho Tribes, is a Native American film director and producer.

Chris Eyre was born in Portland, Oregon, and raised in Klamath Falls by his adoptive parents, Earl and Barbara Eyre. Despite his non-native upbringing, he is an enrolled citizen of the Cheyenne and Arapaho Tribes of Oklahoma. During his time at Klamath Union High School, from which he graduated in 1987, Eyre developed an interest in black-and-white photography, leading him to pursue further education in television production at Mt. Hood Community College in Gresham, Oregon. After completing his studies there, he earned a Bachelor of Arts in Media Arts from the University of Arizona in 1991. His passion for storytelling brought him to New York University Tisch School of the Arts, where he pursued a Master of Fine Arts in filmmaking from 1992 to 1995. His second-year film, Tenacity (1994), garnered attention at various film festivals, including Sundance.

In 1998, Chris Eyre worked on two film projects. His first release was Things We Do (1998). Eyre's breakthrough came with his direction of Smoke Signals (1998), a film developed from a Sundance directing workshop and later bought by Miramar Films. Winning the Sundance Film Festival Filmmakers Trophy and the Audience Award, the film was noted for being the first nationally distributed feature film directed, written, co-produced, and prominently featuring American Indian actors. It also won "Best Film" honors at the 1998 American Indian Film Festival. Eyre described Smoke Signals as a film about the universal theme of forgiveness, which he believed would resonate with audiences for years.

Following his initial success, Eyre directed several other significant films such as Skins (2002), which was shot on the Pine Ridge Reservation, and Edge of America (2003), which won a Peabody Award.

Eyre's second film, Skins (2002), is the story of two brothers on the Pine Ridge Reservation, a tribal cop and a Vietnam vet battling alcohol and emotional problems. He said at a screening: "The only thing you get in making period pieces about Indians is guilt. I'm interested in doing what non-Indian filmmakers can't do, which is portray contemporary Indians."

Eyre's Edge of America (2004) was the 2004 Sundance Film Festival "opening night" film. Edge of America (2004) is loosely based on the true story of a black English teacher who goes to the Three Nations Reservation to teach, but ends up coaching the very underachieving girls basketball team and takes them all the way to the state finals. In the process, he learns as much about their culture and race relations in America as they learn about winning and self-esteem. On January 29, 2006, Eyre won the Directors Guild of America's award for Outstanding Directorial Achievement in Children's Programs for Edge of America, becoming the first Native American to win the award.

Eyre's short film, A Thousand Roads (2005), the "signature film" for the Smithsonian's National Museum of the American Indian, opened in Washington, D.C., on April 10, 2005, for an unlimited and exclusive engagement. It is a contemporary film, following four American Indians in different locations, as they each confront everyday events.

In 2011, Eyre finished Hide Away (2011), collaborating with Salem writer Peter Vanderwal. His work, deeply reflective of his rural, Klamath Falls upbringing, often explores themes beyond Native American stories, focusing on universal human experiences and the spirit of living vicariously through varied characters. The film's cast includes Josh Lucas and Ayelet Zurer.