Charles Robert Knox (April 27, 1932 – May 12, 2018) was an American football coach at the high school, collegiate and professional levels. He served as head coach of three National Football League (NFL) teams, the Los Angeles Rams (1973–1977; 1992–1994), Buffalo Bills (1978–1982), and Seattle Seahawks (1983–1991). He was a three-time AP NFL Coach of the Year and is a member of the Seahawks Ring of Honor.

Knox was born in Sewickley, Pennsylvania, a suburb of Pittsburgh. Whenever Knox felt something was common sense, he said it was "eighth-grade Sewickley."

The son of a steel worker who had emigrated from Ireland and a Scottish-born mother, Knox developed into a 190-pound (86 kg) tackle at Juniata College in Huntingdon, Pennsylvania, playing on both sides of the ball and serving as co-captain of the 1953 unit, the first undefeated team in school history. He also competed in track and graduated in 1954.

Knox then served as an assistant at Juniata that fall. The following year he became an assistant coach at Tyrone High School, then began the first of three years as head coach at Ellwood City High School in 1956.

Building on his success, Knox then moved back to the colleges, serving two seasons as an assistant under Paul Amen at Wake Forest University in 1959. He then joined Blanton Collier's staff at the University of Kentucky in 1961, and stayed the following year under new mentor Charlie Bradshaw. In both these places, Knox learned the concepts of organization, discipline and a focus on fundamentals. While at Kentucky, Knox was on the staff of Bradshaw's infamous first team, which was known forever as the Thin Thirty.

On May 8, 1963, he was hired as offensive line coach of the American Football League's New York Jets by head coach Weeb Ewbank. Over the next four years as the lead contact for recruiting quarterback Joe Namath, Knox helped build a line that protected Namath, eventually leading to a victory over the Baltimore Colts in Super Bowl III. However, by voluntarily leaving the Jets in 1967 he denied himself what would have been the only Super Bowl ring in his career as the Jets won the World Championship in 1968.

Knox then moved to the Detroit Lions on February 13, 1967, under new head coach Joe Schmidt, spending six seasons in the Motor City. Despite some impressive stretches, the Lions reached the postseason only once during this period, losing a 5–0 road contest to the Dallas Cowboys in 1970. However, Knox developed effectively cohesive offensive lines and developed pass-blocking techniques that are now standard in blocking fundamentals. Additionally, he proved a progressive coach by playing Bill Cottrell, an African American, at center. "There was an unwritten rule back then", said Cottrell in Hard Knox: The Life of an NFL Coach. "No black quarterbacks, no black middle linebackers, no black centers." Because of Knox's liberal views and ability to relate to players on such a personal level, African American players nicknamed him, "Dolomite."

When Tommy Prothro was dismissed on January 24, 1973, Knox was hired as head coach of the Los Angeles Rams.