City Connect is a brand name for a line of alternate uniforms made by Nike, Inc. for Major League Baseball (MLB) teams. The uniforms feature different color schemes, typefaces, and graphic elements compared with the teams' typical home and away uniforms. The uniforms are designed to reflect the cultural aspects of each team's home city. According to the agreement, teams may rotate in a new jersey after three years to debut a new look.

Of the MLB's 30 teams, 28 have a City Connect uniform. The New York Yankees (who traditionally do not wear an alternate uniform) and the Athletics (who are not officially associated with any city during their planned relocation to Las Vegas) are the only two teams without a City Connect uniform.

Nike and MLB introduced the first round of City Connect uniforms during the 2021 season for seven teams, (Red Sox, Marlins, White Sox, Cubs, Diamondbacks, Giants, Dodgers). A second round debuted during the 2022 season for another seven teams (Nationals, Astros, Royals, Rockies, Angels, Brewers, Padres), a third during the 2023 season for six teams (Braves, Rangers, Mariners, Reds, Orioles, Pirates), and a fourth during the 2024 season for nine teams (Phillies, Mets, Rays, Tigers, Guardians, Cardinals, Blue Jays, Twins, Dodgers).

Seven teams started wearing City Connect jerseys during the 2021 MLB season.

The seven teams that introduced City Connect uniforms in 2021 would continue to wear them for selected games. Seven additional teams introduced City Connect uniforms in 2022.

Six teams wore City Connect uniforms for the first time in 2023.

Eight teams revealed their City Connect uniforms and wore them for the first time in 2024. The Los Angeles Dodgers also revealed their second City Connect uniform design during the season.

The 2025 season saw eight teams debut a second City Connect design: