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Clare Fowler AI simulator
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Clare Fowler AI simulator
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Clare Fowler
Prof Clare Fowler CBE is a British physician and academic who created the subspecialty of uro-neurology, a medical field that combines urology and neurology. This work was done at the Institute of Neurology, University College London, where she is an emeritus professor.
Early in her career she worked at the Middlesex Hospital and then the National Hospital for Neurology and Neurosurgery, Queen's Square, London, and carried out research in the field of clinical neurophysiology, looking at how nerves work to control the muscles used to control passing urine, work that formed the basis of Fowler's future contributions to continence issues in people with neurological conditions. Her name is given to Fowler's syndrome, a potentially treatable condition in which young women experience urinary retention. With colleagues, she disproved that these women's symptoms were primarily psychological or hysterical and showed that a significant proportion of them could be treated using a type of electrical stimulation therapy, sacral neuromodulation.
In 1987 she established the Department of Uro-Neurology and led trials looking at treatments for urinary retention in women, sildenafil in men with multiple sclerosis and sexual dysfunction, as well as treatments for the symptoms of severe overactive bladders. She assisted with establishing botox detrusor injections as a treatment for people with overactive bladders who did not improve with usual medications.
In 2001 she became professor of Uro-Neurology, and was awarded the British Association of Urological Surgeons's (BAUS) St Peter's Medal in 2010. In 2012 she received the award of Commander the British Empire for services to Uro-neurology.
Her book Pharmacopoeia Londinensis 1618 and its descendants, was published by the Royal College of Physicians in 2018.
Clare Fowler was educated at Wycombe Abbey school, Buckinghamshire, while her parents worked in Bolivia, where her father was a tin ore smelter. She gained admission to study medicine at the Middlesex Hospital Medical School (later merged with University College), and graduated in 1973.
Early in her career, while working for neurologist Pamela Margaret Le Quesne at the Middlesex, she met the then surgical research registrar Roger Kirby, and together they published research articles on how nerves work to control the muscles used to control passing urine, work that formed the basis of Fowler's future contributions to continence issues in people with neurological conditions and earned Kirby an MD. In 1986 they disproved the belief that retention of urine in young women was primarily a psychological or hysterical disorder. By measuring electromyographical signals from the urethral sphincter in these women, they demonstrated that some had a neurophysiological disorder and showed that sacral neuromodulation, a type of electrical stimulation therapy was effective in a significant proportion of them. The condition came to be known as Fowler's syndrome, and is named for her. She later showed that some of these women had associations with hormone imbalances and polycystic ovaries. The response to sacral neuromodulation was impressive and more than two-thirds of these women could pass urine successfully five years after treatment. However many have needed repeated surgery.
In 1976, Fowler took up an appointment as senior house officer at the National Hospital for Neurology and Neurosurgery, Queen's Square, London, (also known as "The National"), where she gained further experience in clinical neurophysiology, looking at the motor and sensory nerve mechanisms of the bladder. Here she worked with neurologists Roman Stefan Kocen, Sir Roger Bannister and Christopher Joseph Earl. Following the advice of Roger William Gilliatt she completed her masters in neurophysiology from University College London, where she also studied laboratory computing and worked with the LINC-8. After a combined part-time consultant post in clinical neurophysiology at the Middlesex and St Bartholomew's Hospital, The National asked her to replace a retiring urologist and appointed her consultant to look after people with conditions such as multiple sclerosis and Parkinson's disease who had bladder problems. At the time, continence issues in people with neurological conditions was not as well understood. A limited control of bladder function was achieved using antimuscarinic medications and self-catheterisation.
Clare Fowler
Prof Clare Fowler CBE is a British physician and academic who created the subspecialty of uro-neurology, a medical field that combines urology and neurology. This work was done at the Institute of Neurology, University College London, where she is an emeritus professor.
Early in her career she worked at the Middlesex Hospital and then the National Hospital for Neurology and Neurosurgery, Queen's Square, London, and carried out research in the field of clinical neurophysiology, looking at how nerves work to control the muscles used to control passing urine, work that formed the basis of Fowler's future contributions to continence issues in people with neurological conditions. Her name is given to Fowler's syndrome, a potentially treatable condition in which young women experience urinary retention. With colleagues, she disproved that these women's symptoms were primarily psychological or hysterical and showed that a significant proportion of them could be treated using a type of electrical stimulation therapy, sacral neuromodulation.
In 1987 she established the Department of Uro-Neurology and led trials looking at treatments for urinary retention in women, sildenafil in men with multiple sclerosis and sexual dysfunction, as well as treatments for the symptoms of severe overactive bladders. She assisted with establishing botox detrusor injections as a treatment for people with overactive bladders who did not improve with usual medications.
In 2001 she became professor of Uro-Neurology, and was awarded the British Association of Urological Surgeons's (BAUS) St Peter's Medal in 2010. In 2012 she received the award of Commander the British Empire for services to Uro-neurology.
Her book Pharmacopoeia Londinensis 1618 and its descendants, was published by the Royal College of Physicians in 2018.
Clare Fowler was educated at Wycombe Abbey school, Buckinghamshire, while her parents worked in Bolivia, where her father was a tin ore smelter. She gained admission to study medicine at the Middlesex Hospital Medical School (later merged with University College), and graduated in 1973.
Early in her career, while working for neurologist Pamela Margaret Le Quesne at the Middlesex, she met the then surgical research registrar Roger Kirby, and together they published research articles on how nerves work to control the muscles used to control passing urine, work that formed the basis of Fowler's future contributions to continence issues in people with neurological conditions and earned Kirby an MD. In 1986 they disproved the belief that retention of urine in young women was primarily a psychological or hysterical disorder. By measuring electromyographical signals from the urethral sphincter in these women, they demonstrated that some had a neurophysiological disorder and showed that sacral neuromodulation, a type of electrical stimulation therapy was effective in a significant proportion of them. The condition came to be known as Fowler's syndrome, and is named for her. She later showed that some of these women had associations with hormone imbalances and polycystic ovaries. The response to sacral neuromodulation was impressive and more than two-thirds of these women could pass urine successfully five years after treatment. However many have needed repeated surgery.
In 1976, Fowler took up an appointment as senior house officer at the National Hospital for Neurology and Neurosurgery, Queen's Square, London, (also known as "The National"), where she gained further experience in clinical neurophysiology, looking at the motor and sensory nerve mechanisms of the bladder. Here she worked with neurologists Roman Stefan Kocen, Sir Roger Bannister and Christopher Joseph Earl. Following the advice of Roger William Gilliatt she completed her masters in neurophysiology from University College London, where she also studied laboratory computing and worked with the LINC-8. After a combined part-time consultant post in clinical neurophysiology at the Middlesex and St Bartholomew's Hospital, The National asked her to replace a retiring urologist and appointed her consultant to look after people with conditions such as multiple sclerosis and Parkinson's disease who had bladder problems. At the time, continence issues in people with neurological conditions was not as well understood. A limited control of bladder function was achieved using antimuscarinic medications and self-catheterisation.