Clinofibrate (INN; trade name Lipoclin) is pharmaceutical drug of the fibrate class that is used for managing hyperlipidemia and associated conditions. It is sold and marketed in Japan.

Chemically, it is a derivative of bisphenol Z.

The condensation between cyclohexanone (1) and phenol (2) gives bisphenol Z (3). This is treated with chloroform and methyl ethyl ketone (MEK) in the presence of base. The resulting Bargellini reaction gives clinofibrate (4).