The Coordinated Science Laboratory (CSL) is a major multidisciplinary scientific research laboratory in the Grainger College of Engineering at the University of Illinois Urbana-Champaign. With deep roots in information technology, CSL has invented and deployed many landmark innovations, such as the electric vacuum gyroscope, the first computer-assisted instructional program, and the plasma screen. Today, key research areas include applied research and technology; circuits; computational and physical electronics; computer systems and architecture; decision and control; intelligent sensing, networking, and cyber-physical systems; remote sensing and space science; robotics; security and privacy; signals, inference, and networks; societal impacts of technology; and more.

Established during the Korean War in 1951 as a classified military-research laboratory called the Control Systems Laboratory, CSL was originally intended to focus on automated control systems, with a major focus on radar. In 1959 it switched to a much broader civilian-oriented research mission and was renamed the Coordinated Science Laboratory.

Research at CSL is led by about 150 faculty members spanning over 15 departments and schools at the University of Illinois Urbana-Champaign, with over 250 current graduate student researchers.

CSL receives funding from a wide range of federal, state, and private sources.