Marvel Comics announced that Crystal Frasier would co-write the comic series 'Gamma Flight' with Al Ewing, with illustrations by Lan Medina. This project further establishes her presence in the world of mainstream comic book writing, contributing to a series within the Marvel Universe. She had previously worked for Marvel in 2020 on a comic about The Immortal Hulk.

DC Comics announced that Crystal Frasier would be one of the writers for the 'Love Is a Battlefield' special. She collaborated with Juan Gedeon on a story involving Wonder Woman and Steve Trevor. This announcement signifies her expansion into mainstream comic book writing, working on established characters within a major comic book publisher.