Cynognathia ("dog jaw") is one of two major clades of cynodonts, the other being Probainognathia. Cynognathians included the large carnivorous genus Cynognathus and the herbivorous or omnivorous gomphodonts such as traversodontids. Cynognathians can be identified by several synapomorphies including a very deep zygomatic arch that extends above the middle of the orbit.

Cynognathian fossils are currently known from Africa, Antarctica, Asia, Europe, North America and South America.

Cynognathians in a cladogram after Stefanello et al. (2023):