David Livingstone (/ˈlɪvɪŋstən/; 19 March 1813 – 1 May 1873) was a Scottish doctor, Congregationalist, pioneer Christian missionary with the London Missionary Society, and an explorer in Africa. Livingstone was married to Mary Moffat Livingstone, from the prominent 18th-century Moffat missionary family. Livingstone came to have a mythic status as a Protestant missionary martyr, working-class "rags-to-riches" inspirational story, scientific investigator and explorer, imperial reformer, anti-slavery crusader, and advocate of British commercial and colonial expansion. As a result, he became one of the most popular British heroes of the late 19th-century Victorian era.

Livingstone's fame as an explorer and his obsession with learning the sources of the Nile was founded on the belief that if he could solve that age-old mystery, his fame would give him the influence to end the East African Arab–Swahili slave trade. "The Nile sources", he told a friend, "are valuable only as a means of opening my mouth with power among men. It is this power [with] which I hope to remedy an immense evil." His subsequent exploration of the central African watershed was the culmination of the classic period of European geographical discovery and colonial penetration of Africa. At the same time, his missionary travels, "disappearance" and eventual death in Africa‍—‌and subsequent glorification as a posthumous national hero in 1874‍—‌led to the founding of several major central African Christian missionary initiatives carried forward in the era of the European "Scramble for Africa", during which almost all of Africa fell under European rule for decades.

Livingstone was born on 19 March 1813 in the mill town of Blantyre, Scotland, in a tenement building for the workers of a cotton factory on the banks of the River Clyde under the bridge crossing into Bothwell. He was the second of seven children born to Neil Livingstone and his wife Agnes (née Hunter).

David was employed at the age of ten in the cotton mill of Henry Monteith & Co. in Blantyre Works. He and his brother John worked 14-hour days as piecers, tying broken cotton threads on the spinning machines.

Neil Livingstone was a Sunday school teacher and teetotaller who handed out Christian tracts on his travels as a door-to-door tea salesman. He read books on theology, travel, and missionary enterprises extensively. This rubbed off on the young David, who became an avid reader, but he also loved scouring the countryside for animal, plant, and geological specimens in local limestone quarries. Neil feared that science books were undermining Christianity and attempted to force his son to read nothing but theology, but David's deep interest in nature and science led him to investigate the relationship between religion and science. In 1832, he read Philosophy of a Future State, written by Thomas Dick, and he found the rationale that he needed to reconcile faith and science and, apart from the Bible, this book was perhaps his greatest philosophical influence.

Other significant influences in his early life were Thomas Burke, a Blantyre evangelist, and David Hogg, his Sunday school teacher. At age fifteen, David left the Church of Scotland for a local Congregational church, influenced by preachers like Ralph Wardlaw, who denied predestinarian limitations on salvation. Influenced by revivalistic teachings in the United States, Livingstone entirely accepted the proposition put by Charles Finney, Professor of Theology at Oberlin College, Ohio, that "the Holy Spirit is open to all who ask it". For Livingstone, this meant a release from the fear of eternal damnation. Livingstone's reading of missionary Karl Gützlaff's Appeal to the Churches of Britain and America on behalf of China enabled him to persuade his father that medical study could advance religious ends.

Livingstone's experiences in H. Monteith's Blantyre cotton mill were also important from ages 10 to 26, first as a piecer and later as a spinner. This monotonous work was necessary to support his impoverished family, but it taught him persistence, endurance, and a natural empathy with all who labour, as expressed by lines that he used to hum from the egalitarian Robert Burns song: "When man to man, the world o'er/Shall brothers be for a' that".

Livingstone attended Blantyre village school, along with the few other mill children with the endurance to do so despite their 14-hour workday (6 am–8 pm). Having a family with a strong, continuing commitment to study reinforced his education.