Margaret Jane "Dee Dee" Myers (born September 1, 1961) is an American political analyst who served as the 19th White House Press Secretary during the first two years of the Clinton administration. She was the first woman and, at the time, the second-youngest person to hold that position. Myers later co-hosted the news program Equal Time on CNBC, and was a consultant on The West Wing. She was the inspiration for fictional White House Press Secretary C. J. Cregg. She is also the author of the 2008 New York Times best-selling book, Why Women Should Rule the World. In 2020, she joined the Gavin Newsom administration as Senior Advisor to the Governor and Director of the Governor's Office of Business and Economic Development.

Margaret Jane Myers was born in 1961 at Quonset Point in North Kingstown, Rhode Island, to Stephen and Judy Myers. Her nickname, "Dee Dee", originated when her sister could not pronounce "baby."

Myers spent most of her formative years in Valencia, Santa Clarita, California. Her father was a Navy aviator who completed two tours of duty in the Vietnam War, and her mother worked as a real estate agent.

Myers is a graduate of William S. Hart High School and Santa Clara University (1983).

Myers met her husband, Todd Purdum, the national editor for Vanity Fair, former White House correspondent, and Los Angeles bureau chief for The New York Times, during the 1992 presidential campaign. The couple, who married in 1997, have two children, Kate and Stephen, and live in Los Angeles, California.

Myers' career in political communications began shortly after graduating from college, taking a full-time role on the 1984 presidential campaign of Walter Mondale. She later served as a field representative for California State Senator Art Torres, and as assistant press secretary in the office of Los Angeles Mayor Tom Bradley and on his 1986 campaign for California governor. She was also a spokesperson for Michael Dukakis' 1988 presidential bid and Dianne Feinstein's 1990 California gubernatorial campaign, and served as campaign manager for Frank Jordan's 1991 run for San Francisco mayor.

Myers joined Bill Clinton's presidential campaign team in 1991 and, following the 1992 presidential election, was named Clinton's first White House Press Secretary, a role she held from January 20, 1993, to December 22, 1994. She was the first woman to serve in that position and was the second-youngest, behind Ron Ziegler, when she took the job at the age of 31. Myers is now the third-youngest, as Karoline Leavitt, Donald Trump's press secretary, was 27 when she assumed the role in January 2025.

According to the Detroit Free Press, Myers earned a reputation for her "humor and patience" in handling the White House press corps, often delivering "quick one-liners" while issuing daily press briefings. Until September 1994, when she was given the title of Assistant to the President, she held the lesser title of "deputy assistant" and had a lower salary than previous White House Press Secretaries. She also lacked consistent access to Clinton's inner circle. This was frequently noted in news coverage about Myers throughout her term, and is addressed in her 2008 book, Why Women Should Rule The World.