Deulumateperone (INNTooltip International Nonproprietary Name; developmental code name ITI-1284) is an experimental antipsychotic of the pyridopyrroloquinoxaline and butyrophenone families as well as a deuterated analogue of lumateperone which is under development as a sublingually administered orally disintegrating tablet (ODT) for the treatment of psychotic disorders, agitation, and generalized anxiety disorder. No recent development has been reported for treatment of depressive disorders, behavioral disorders, and dementia. It is being developed by Intra-Cellular Therapies. As of January 2025, it has reached phase 2 clinical trials.