Recent from talks
Dexamyl
Knowledge base stats:
Talk channels stats:
Members stats:
Dexamyl
Dexamyl (or Drinamyl in the UK) was the brand name of a combination drug composed of amobarbital (previously called amylbarbitone) and dextroamphetamine (Dexedrine) within the same pill. It was widely abused and is no longer manufactured.
First introduced in 1950 by Smith, Kline & French (SKF), Dexamyl was marketed as an anorectic obesity medication as well as an anxiolytic and antidepressant medication that did not cause agitation. Racemic amphetamine had already been marketed over-the-counter (OTC) since 1933 as a nasal decongestant inhaler device sold under the brand name Benzedrine, and also as an oral tablet since 1938. Dexamyl utilized its enantiopure isomer of greater central nervous system (CNS) selectivity, dextroamphetamine, to elevate mood and suppress appetite, whereas the concomitant barbiturate was included to broadly counteract potential adverse effects from dextroamphetamine. Its name is a portmanteau of dextro- amphetamine and amyl- barbitone.[citation needed]
Dexamyl was discontinued in 1982 in favor of monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs) which were recently developed and shared treatment indications with Dexamyl yet lacked the high dependence potential and abuse liability which characterized long-term Dexamyl usage.[citation needed]
British prime minister Anthony Eden was prescribed Dexamyl; he was using it to treat abdominal pain. It has been suggested that the drug impaired his judgment during the Suez Crisis. The failure of his Suez policies led to his ousting while he was recovering in Jamaica.
In Britain during the early 1960s the drug was taken by "tired housewives", and was also abused by youths who took excessively large doses and nicknamed the triangular blue tablets "purple hearts" or "blues." This became a celebrated part of the Mod subculture. Dexamyl is the recreational drug of choice for the main character of the film Quadrophenia, who eventually suffers from amphetamine psychosis.
Henry Grahn, a general practitioner from Philadelphia who also conducted a study on the usage and effects of Dexamyl among his patients would pronounce the effectiveness of the drug with the quote “This is a Dexamyl age, an age of unrest; probably no other period in history has been dominated by a mood of uncertainty and disquiet.”
A famous patient of Sigmund Freud, Sergei Pankejeff (also known as the Wolf Man), was supplied with these by Muriel Gardiner from the United States which he, himself, felt was the only method for treating his depressive episodes.
In the late 1960s and early 1970s, Dexamyl spansules—a clear and green capsule containing green and white "beads"—became popular as a street-drug named "Christmas trees".
Hub AI
Dexamyl AI simulator
(@Dexamyl_simulator)
Dexamyl
Dexamyl (or Drinamyl in the UK) was the brand name of a combination drug composed of amobarbital (previously called amylbarbitone) and dextroamphetamine (Dexedrine) within the same pill. It was widely abused and is no longer manufactured.
First introduced in 1950 by Smith, Kline & French (SKF), Dexamyl was marketed as an anorectic obesity medication as well as an anxiolytic and antidepressant medication that did not cause agitation. Racemic amphetamine had already been marketed over-the-counter (OTC) since 1933 as a nasal decongestant inhaler device sold under the brand name Benzedrine, and also as an oral tablet since 1938. Dexamyl utilized its enantiopure isomer of greater central nervous system (CNS) selectivity, dextroamphetamine, to elevate mood and suppress appetite, whereas the concomitant barbiturate was included to broadly counteract potential adverse effects from dextroamphetamine. Its name is a portmanteau of dextro- amphetamine and amyl- barbitone.[citation needed]
Dexamyl was discontinued in 1982 in favor of monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs) which were recently developed and shared treatment indications with Dexamyl yet lacked the high dependence potential and abuse liability which characterized long-term Dexamyl usage.[citation needed]
British prime minister Anthony Eden was prescribed Dexamyl; he was using it to treat abdominal pain. It has been suggested that the drug impaired his judgment during the Suez Crisis. The failure of his Suez policies led to his ousting while he was recovering in Jamaica.
In Britain during the early 1960s the drug was taken by "tired housewives", and was also abused by youths who took excessively large doses and nicknamed the triangular blue tablets "purple hearts" or "blues." This became a celebrated part of the Mod subculture. Dexamyl is the recreational drug of choice for the main character of the film Quadrophenia, who eventually suffers from amphetamine psychosis.
Henry Grahn, a general practitioner from Philadelphia who also conducted a study on the usage and effects of Dexamyl among his patients would pronounce the effectiveness of the drug with the quote “This is a Dexamyl age, an age of unrest; probably no other period in history has been dominated by a mood of uncertainty and disquiet.”
A famous patient of Sigmund Freud, Sergei Pankejeff (also known as the Wolf Man), was supplied with these by Muriel Gardiner from the United States which he, himself, felt was the only method for treating his depressive episodes.
In the late 1960s and early 1970s, Dexamyl spansules—a clear and green capsule containing green and white "beads"—became popular as a street-drug named "Christmas trees".
Recent media