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Dynorphin A
Dynorphin A is a dynorphin, an endogenous opioid peptide that activates the κ-opioid receptor. Its amino acid sequence is Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys (YGGFLRRIRPKLK), a tridecapeptide.
Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile (YGGFLRRI). Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta-opioid receptors; it has the highest binding affinity for the kappa-opioid receptor. Structures of dynorphin A bound to the κ-opioid receptor have been reported.
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Dynorphin A
Dynorphin A is a dynorphin, an endogenous opioid peptide that activates the κ-opioid receptor. Its amino acid sequence is Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys (YGGFLRRIRPKLK), a tridecapeptide.
Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile (YGGFLRRI). Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta-opioid receptors; it has the highest binding affinity for the kappa-opioid receptor. Structures of dynorphin A bound to the κ-opioid receptor have been reported.