East Selkirk is a community of 675 (2016 Census) in the Rural Municipality (RM) of St. Clements in the Canadian province of Manitoba. It is directly across the Red River from Selkirk, Manitoba.

The village of East Selkirk is connected to Winnipeg, about 41 kilometres (25 mi) away, via Highway 59 or Provincial Road 204

The Town of East Selkirk was incorporated in 1883 and its first reeve was Francis Hay. East Selkirk saw a huge immigration boom in the latter part of the 19th century and the early part of the 20th century. The Round House, a large building made of Tyndall limestone, was situated next to the railway tracks and not only served as an immigration hall but also as the church, school and hospital. Many immigrants from Poland, Ukraine and other eastern-European countries passed through its doors and onward to their homesteads throughout the Interlake, but some remained to settle in the local area.

East Selkirk was also home to the St. Peter's Reservation. It was here that Chief Peguis led his Saulteaux tribe in the early 19th century. Beginning in the late 1890s, the village of East Selkirk, as well as the town of Selkirk, Manitoba, Rural Municipality of St. Clements and St. Andrew's, Manitoba slowly began incorporating the lands of the Reservation and taxing the British-European occupants who held patents to river lots. This began a dispute that ultimately led the Federal Department of Indian Affairs to force the Saulteaux people out to clear way for the British-European settlers. Federal Agents came to the Reserve, bribed the Chief and Band Council, got them drunk and gave the entire tribe only one day to decide on the surrender agreement. In 1907, the surrender took place and the Saulteaux were moved to a remote corner of Lake Winnipeg to join the Peguis Reserve. This surrender was, and still is, considered illegal. Peguis First Nation finalized a land claim in 2008 that originated from this incident.

A bridge connecting the two communities was planned for construction in 1931, but the Depression delayed the project. In the fall of 1936 the bridge connecting the village of East Selkirk to the City of Selkirk was opened. At the time it cost more than C$300,000 to build.

The Town of East Selkirk was dissolved in 1904 and the community absorbed by the neighboring RM of St. Clements. The RM celebrated its centennial anniversary in 1884.

The village is home to an elementary school, Happy Thought School and a junior high, East Selkirk Middle School. The mascot of Happy Thought School is a husky and the mascot of East Selkirk Middle School is a hawk. The village is also home to the East Selkirk Recreation Association, a post office, gas station, and also two churches: St. Stanislaus Roman Catholic Church and the Blessed Virgin Mary Ukrainian Catholic Church.

The Central Manitoba Railway (CEMR), owned by Cando Rail Services Ltd. of Brandon, operates a 108 kilometres (67 mi) short line between East Selkirk and Carman, In 2018 they were given C$5.6 million to improve rail service between the two communities.