Echogenetic is the fifteenth full-length studio album by Vancouver industrial band Front Line Assembly, released on July 9, 2013. It was well received both by critics and fans and charted in German and US charts. Critics commented on the band's return to a purely electronic approach and on the dubstep influence on the album. Front Line Assembly toured extensively in Europe and North America in support of this album and remix follow-up Echoes, which included a tour with vocalist and band leader Bill Leeb's former band Skinny Puppy. This was the last studio album to feature Jeremy Inkel before his death in 2018.

Bill Leeb called predecessor album AirMech a "really cool warm-up" for the production of Echogenetic and added: "We just thought we should just continue on and evolve and keep that going for the new Front Line record."

Leeb also commented on the fact that the writing process in the band changed with the growing number of writers. "In the really early days it was just me and Rhys and then me and Chris", Leeb said, comparing the situation with the current composer line-up: "This time there were five of us: Jeremy [Inkel] and his friend Sasha [Keevill] were in one camp, and then Jared [Slingerland] and his right hand guy Craig [Johnsen] were in the other camp." The process involved Leeb "jumping between two studios" and the group getting together "every two or three weeks and critique everything, go over things" and "add new elements to each others' work." Leeb expressed his relief that more shoulders than in past line-ups shared the workload.

For the first time in their history the band set a deadline for an album to be completed. The band broke new ground for themselves with their style of songwriting. "With the new stuff, there's a process called ducking and chaining", explained Leeb, "it's focusing more on the actual sound and timing of it." According to Leeb, "it's what makes it sound different and interesting." In contrast to the experimental nature of the writing process, Leeb called the abandoning of guitars "really my only conscious effort this time." The reason for this decision was to "just go back to what influenced me when I started Front Line."

Advancements in computer technology influenced the songwriting as well. Leeb stated that the use of virtual synthesizers and other software simplified composing, and since the band need not enter a recording studio, made production more affordable. This affected the working routine with long-time engineer and mixer Greg Reely: "With this new record, [...] when we have songs we'd send them to Greg, he would mix and send them back and we'd spend a week listening and be 'well, we like this' and 'we want to change that'." Leeb emphasized the role Reely played in producing Echogenetic, saying, "when you work with him for over 25 years it just like with every good relationship, it just evolves." Thus Leeb considered Reely's work "a big bonus for us."

Front Line Assembly revealed the album title on their official Twitter account on February 23, 2013, writing the title's letters in reverse order. First announcements of the release date stated Echogenetic was to be released early August or July 2013. In the wake of these announcements the band made further details of Echogenetic available. In April 2013 the cover and the track list were revealed. Metropolis published an excerpt of track "Prototype" as preview in June and followed up with full versions of tracks "Killing Grounds" and "Ghosts" shortly after. One day before release, Revolver magazine released the complete album as SoundCloud stream.

Echogenetic was released in various formats. Metropolis issued the album on CD and as digital download. Dependent offered a broader range of formats. The CD version was released as limited edition digipak and in regular jewel case while the vinyl version came with two LPs in gatefold and a download code. The vinyl edition was also offered as part of a fan bundle that included a worker shirt. A fan edition that included the CD and an exclusive band T-shirt was available in Germany.

With the release the band announced a remix album.