Edward Michel Khayat (September 14, 1935 – December 6, 2024) was an American professional football player and coach in the National Football League (NFL). He spent 10 years as a player (117 game total) and 25 as a coach. He was a starting defensive tackle for the champion Philadelphia Eagles in the 1960 NFL Championship Game and later their head coach in 1971 and 1972. He is a member of six Halls of Fame. He also served on the Former Players Board of Directors of the National Football League Players Association (NFLPA).

Khayat attended Moss Point High School in Moss Point, Mississippi, from 1949 to 1953, where he lettered in football (2), basketball (3), and baseball (3).

In 1953, Khayat attended Millsaps College, where he lettered in football and basketball. In 1954, he won the Mississippi Golden Gloves Heavyweight Championship (novice class).

Also in 1954, he won a scholarship to Perkinston Junior College (Mississippi Gulf Coast Community College), where he lettered in football and basketball.

In 1955, he was awarded a scholarship to Tulane University where he lettered in football (2) and baseball (1). He was elected to the All-Time Tulane Green Wave football team in 1979 and the Tulane Green Wave football All-Century Team in 1993.

In 1957, he was signed as a free agent by the Washington Redskins. His playing career spanned ten years until his retirement after the 1966 season with the Boston Patriots. The bulk of his career was spent with the Philadelphia Eagles, where he was the starting defensive tackle for the 1960 World Championship team.

After his retirement from playing, Khayat began his twenty-five-year career in the National Football League as a coach. In 1967, he became the first defensive line coach for the expansion New Orleans Saints, where he coached future Hall of Famer Doug Atkins. In his next stop with the Philadelphia Eagles (1971–1972), he was named Head Coach three games (after Jerry Williams was fired) into the season and rallied the team to a 6-4-1 finish. In an interesting sidelight, he imposed a draconian hair and dress code on the Eagles players during his stint with the Eagles, leading to widespread resentment, including linebacker Tim Rossovich demanding, and getting, a trade (to the San Diego Chargers). In the run-up to the team's November 26, 1972, game against the New York Giants, Khayat "guaranteed" that the Eagles would win the game, despite the fact that the Eagles were a 14-point underdog. The Giants won the game 62-10, and it was widely believed that this sealed his fate in Philadelphia. Three weeks later, after a loss to the St. Louis Cardinals meant that the Eagles finished last in the NFC East, Khayat was fired the next day.

Khayat coached hall of famer Claude Humphrey, (who later played for the Eagles) during his stint as an assistant coach with the Atlanta Falcons (1975–1976). He was also the defensive line coach for the AFC East Champion Baltimore Colts (1977), the AFC Champion New England Patriots (1985) and the AFC East Champion New England Patriots (1986).