The Epitaphios Thrinos (Greek: Επιτάφιος Θρήνος, lit. 'Threnody on the Tomb') also known as Encomia Epitafiou (Εγκώμια Επιταφίου) is a Christian liturgical hymn sang on Holy Friday in the Orthodox churches. Full of strong emotional feelings, it is one of "the most beloved hymns of the Orthodox".

Known in English as the "Threnody at the Tomb", its other Greek name, Encomia Epitafiou (Greek: Εγκώμια επιταφίου), "Praises of the Tomb", could assimilate it with a form of encomium or praise rather than lament. The pagan encomium is the source of the Christian panegyric, and the Epitaphios Thrinos was therefore a form of panegyric for Christ.

The early manuscripts for the liturgy of Holy Saturday do not seem to mention the Encomia. The first reference to encomia is found in manuscripts of the thirteenth century in connection with Psalm 118, known as the Amomos. Their number, however was undefined, and it appears that the collection grew gradually to its present form, resulting in many variations among the collections.

The repertoire of the Encomia lamentations first appeared as such in the 1522 edition of the service book of the Orthodox Church Triodion, printed in Venice. Subsequent editions have relied heavily on this source.

According to the Lenten Triodion as well as the 1906 edition of the Patriarchal Text, there are 185 verses in the Epitaphios Thrinos divided into three stasis or sections. However, the Triodion and the Patriarchal text do not concur as to the placement of the Epitaphios: in all the editions of the Triodion the Encomia appear before the Canon in the order of the Orthros of Great Saturday while the same Encomia appear after the Canon for the Patriarchal Text of Great Week.

The verses of these Lamentations are interspersed between the verses of Psalm 118 (the chanting of this psalm forms a major part of the Orthodox funeral service as well as being a usual part of Saturday Matins). The Lamentations are divided into three sections called stáses, which commemorate the Passion, Death and Entombment of Christ. Each statis is commonly known by its first phrase; in Greek these are:

At the beginning of each stasis, the priest or deacon performs a censing of the epitaphios. In the Greek tradition, at the third and final stasis, the priest will sprinkle rosewater on the epitaphios and the congregation, symbolising the anointing of Christ's body with spices.

All three of stasis end with the same eulogy they begin while the officiating priest or high priest incenses the epitaph on all four sides.