Eugene Jackson (born September 23, 1966) is an American former mixed martial artist who competed in the middleweight division of the Ultimate Fighting Championship and Strikeforce. Jackson was the only Strikeforce U.S. Middleweight Champion.

Jackson compiled a professional mixed martial arts record of 9-3-1 that included winning the Bas Rutten Invitational 1 Middleweight tournament over Joe Doerksen as well as losing to future Pride Middleweight Champion, Wanderlei Silva whilst competing for the IVC Cruiserweight Championship before signing for UFC in 1999.

Jackson made his UFC debut at middleweight on July 16, 1999, against Royce Alger at UFC 21. He won the fight via KO with punches in the second round.

Jackson then faced Keiichiro Yamamiya on November 19, 1999, at UFC 23. He won the fight via KO with a punch in the third round.

Jackson then faced Sanae Kikuta on April 14, 2000, at UFC 25. He lost the fight via an armbar submission in the first round.

Jackson then faced Jeremy Horn on September 22, 2000, at UFC 27. He lost the fight via an armbar submission in the first round.

Jackson then faced Ricardo Almeida on September 28, 2001, at UFC 33. He lost the fight via a triangle choke submission in the first round.

Jackson then faced Keith Rockel on January 11, 2002, at UFC 35. He won the fight via a guillotine choke submission in the second round thus snapping a three-fight losing streak.