Eunice conducted groundbreaking experiments using an air pump, glass cylinders, thermometers, and sunlight to investigate the effects of solar radiation on different gases. She observed that carbon dioxide trapped more heat than air and hypothesized that changes in atmospheric carbon dioxide could affect global temperature.

Foote's paper, 'Circumstances Affecting the Heat of the Sun's Rays,' was presented at the eighth annual AAAS meeting in Albany, New York. Joseph Henry of the Smithsonian Institution presented it on her behalf, as it was uncommon for women to present their own work at the time. Although the precise wording of Henry's presentation is lost, it is assumed he accurately described the experiments and their findings.

Foote's research paper was published in the prestigious "American Journal of Science and Arts". This publication ensured her work reached a wider scientific audience, establishing her as a recognized voice in scientific discourse.

Eunice published a second paper in the "Philosophical Magazine" about the electrical excitement of the vaporation of water. The paper was based on her own research and testing.