Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene.

LIM proteins are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.

FHL3 plays a role in myogenesis, and also stimulates the development of neural crest by enhancing BMP signaling.

FHL3 has been shown to interact with:

This article incorporates text from the United States National Library of Medicine, which is in the public domain.