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Factorial experiment

In statistics, a factorial experiment (also known as full factorial experiment) investigates how multiple factors influence a specific outcome, called the response variable. Each factor is tested at distinct values, or levels, and the experiment includes every possible combination of these levels across all factors. This comprehensive approach lets researchers see not only how each factor individually affects the response, but also how the factors interact and influence each other.

Often, factorial experiments simplify things by using just two levels for each factor. A 2x2 factorial design, for instance, has two factors, each with two levels, leading to four unique combinations to test. The interaction between these factors is often the most crucial finding, even when the individual factors also have an effect.

If a full factorial design becomes too complex due to the sheer number of combinations, researchers can use a fractional factorial design. This method strategically omits some combinations (usually at least half) to make the experiment more manageable.

These combinations of factor levels are sometimes called runs (of an experiment), points (viewing the combinations as vertices of a graph), and cells (arising as intersections of rows and columns).

Factorial designs were used in the 19th century by John Bennet Lawes and Joseph Henry Gilbert of the Rothamsted Experimental Station.

Ronald Fisher argued in 1926 that "complex" designs (such as factorial designs) were more efficient than studying one factor at a time. Fisher wrote,

"No aphorism is more frequently repeated in connection with field trials, than that we must ask Nature few questions, or, ideally, one question, at a time. The writer is convinced that this view is wholly mistaken. Nature, he suggests, will best respond to a logical and carefully thought out questionnaire; indeed, if we ask her a single question, she will often refuse to answer until some other topic has been discussed."

A factorial design allows the effect of several factors and even interactions between them to be determined with the same number of trials as are necessary to determine any one of the effects by itself with the same degree of accuracy.

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experiment whose design consists of two or more factors, each with discrete possible values, and whose experimental units take on all possible combinations of these levels across all such factors
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