Fierce Creatures is a 1997 farcical comedy film. While not literally a sequel, Fierce Creatures is a spiritual successor to the 1988 film A Fish Called Wanda. Both films star John Cleese, Jamie Lee Curtis, Kevin Kline and Michael Palin. Fierce Creatures was written by John Cleese and directed by Robert Young and Fred Schepisi. The film was dedicated to Gerald Durrell and Peter Cook. Some scenes were filmed at Jersey Zoo, a zoological park founded by Durrell.

Willa Weston arrives in Atlanta to take a high-ranking position in a company recently acquired by Octopus Inc.'s owner, Rod McCain. When he informs her he has already sold the company, she then agrees to run another recent acquisition, Marwood Zoo. She is to create a business model that can be used for multiple zoos in the future. Rod McCain's son Vincent, who is attracted to Willa, announces that he will join her at the zoo. The zoo's newly appointed director is a retired Hong Kong Police Force officer and former Octopus Television employee, Rollo Lee. To meet Octopus's revenue target of 20% from all assets, he institutes a "fierce creatures" theme. Believing dangerous and violent animals will attract more visitors, all animals not meeting those requirements must go.

All the animal keepers, including spider-handler Bugsy, try to change Rollo's mind. One such attempt involves getting him to kill some of the cutest animals himself, but Rollo sees through their prank and fakes the animals' extermination. He keeps the animals in his bedroom which later causes Willa and Vincent to believe he is having an orgy with female staff. Rollo discovers that several staff members are faking animal attack injuries. He fires several warning shots at those responsible and Reggie rushes in, believing that one of them is shot. Rollo then finds a visitor who has had a genuine accident but, not believing it is real, tastes her blood whilst loudly proclaiming that it is fake. Willa and Vincent, upon seeing this fiasco, demote Rollo to middle management. Vince even threatens to fire him if he does not cease his apparent activities with the female staff.

Vince covers both the zoo and animals alike with advertisements after garnering sponsors, dresses the staff in ridiculous outfits, and installs an artificial panda in one of the enclosures. His continued attempts to seduce Willa fail, while she comes to enjoy working at the zoo after connecting with a silverback gorilla. Willa finds herself attracted to Rollo after becoming fascinated by his apparent ability to attract multiple women. When he tries to discuss Vince's marketing plan, she suggests dinner, but she postpones when she remembers Rod is coming from Atlanta to discuss the running of the zoo.

Worried that the visit might be part of a plan to close the zoo, Rollo and the zookeepers bug Rod's hotel room to find out. Although the plan goes awry, they discover he wants to sell it to Japanese investors who'll turn it into a golf course. Also, he plans to have himself cryogenically frozen whenever he gets ill so Vince would never inherit anything. Discovering Vince has stolen sponsorship money he raised, Willa warns him to return it, or she will tell Rod. As Rollo attempts to work out how the theft can be traced, he and Willa finally kiss, just as Vince arrives to return the money. A confrontation then ensues as Willa, Rollo, Bugsy, and several others attempt to stop Vince from running off with the money.

Rod arrives just as Vince, who is holding a gun, is being subdued and announces the police are on their way to arrest him for stealing. Vince tries and fails to shoot his father, but then Bugsy takes the pistol and accidentally shoots Rod between the eyes. In the panic that follows, a plan emerges to fool Neville, Rod's business associate, and the arriving police. The keepers work together to dress Vince up as Rod, as he can imitate his father's accent fairly well. When they arrive, Vince (as Rod) tells them that he has rewritten the will, specifying that the zoo will become a trust for the caretakers while Vince will inherit everything else, and he asks all of them to be witnesses.

After signing the new will, Vince locks himself in a caretaker hut where they fake Rod's suicide. Although Neville becomes suspicious, he is left dumbstruck when he finds his boss's dead body in the hut. Now free, the zookeepers destroy the evidence of McCain's ownership. Vince becomes the new CEO of Octopus, while Willa and Rollo happily begin a new life together while continuing to run the zoo.

The movie was based on a sketch written by Palin and Terry Jones in 1967 for Comedy Playhouse about a zoo that is taken over by a man who just wants to stock it with dangerous animals. Cleese began writing the script in 1992 and shooting began on 15 May 1995. The first director was Robert Young who had previously made commercials with Cleese. Ronnie Corbett later recalled in his memoir that the shoot "was a struggle from the start. There is always a sort of gloom and a feeling of unease on a film set when the words are not quite right, and, in this case, there were too many good people in the film with not enough for them to do. It was difficult for the director Robert Young because everyone was coming up with new ideas all the time and trying to give him guidance."