Fraxel Laser Treatment is a line of lasers developed by Reliant Technologies in 2004. It was developed from a US patent licensed from the Wellman Center for Photomedicine. R. Rox Anderson was the inventor. Fraxel lasers cause fractional photothermolysis for skin resurfacing.

Complications observed in a study of 961 fractional laser treatments included acne and herpes outbreaks. There have also been anecdotal negative accounts of bad scarring and hyperpigmentation following the use of Fraxel lasers.

Fraxel laser is used primarily to rejuvenate skin. It is used to treat hyperpigmentation, dark spots, and superficial signs of aging such as fine lines and wrinkles, as well as acne scarring.

Several variations of Fraxel lasers exist, each with distinct characteristics. These systems are distinguished by their laser types and the depth of tissue ablation they achieve.