Fred August Enke (July 12, 1897 – November 2, 1985) was an American football and basketball player, coach of football, basketball, baseball, and golf, and college athletics administrator. The Rochester, Minnesota native coached basketball for two seasons at the University of Louisville (1923–1925) and 36 seasons at the University of Arizona (1925–1961), compiling a career college basketball record of 522–344 (.603). Enke also spent two seasons as head football coach at Louisville (1923–1924) and one season as the head football coach at Arizona (1931), tallying a career college football mark of 11–13–2. In addition, he was the head baseball coach at Louisville for two seasons (1924–1925) and the school's athletic director from 1923 to 1925. Enke's son, Fred William Enke, played seven seasons in the National Football League (NFL).

The street Enke Drive, on the University of Arizona campus is named in honor of Fred A. Enke. There is also the Fred Enke golf course in far eastern Tucson.