Fred Flintstone and Friends is an American animated anthology wheel series and a spin-off of The Flintstones produced by Hanna-Barbera and Columbia Pictures Television that aired in daily first-run syndication from September 12, 1977, to September 1, 1978. The series was packaged by Columbia Pictures Television during the 1977–78 television season and was available for barter syndication through Claster Television through the mid-1980s.

Henry Corden made his official debut as Fred Flintstone's speaking voice on this series after Alan Reed died in June 1977. Corden had previously appeared as Fred's singing voice in the theatrical film The Man Called Flintstone (1966) and the television specials Alice in Wonderland or What's a Nice Kid like You Doing in a Place like This? (1966) and Energy: A National Issue (1977). He continued providing Fred's voice in future Flintstones spin-off series and specials, as well as Cocoa Pebbles and Fruity Pebbles cereal commercials, until his death in 2005.

The series is hosted by Fred Flintstone and featured a repackaging of the following six Hanna-Barbera Saturday morning cartoons that were originally broadcast by the various networks:

The following segments were broadcast in odd weeks:

The following segments were broadcast in even weeks: