Fructose-bisphosphatase 2 is an enzyme that in humans is encoded by the FBP2 gene.

This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 2,6-bisphosphate to fructose 6-phosphate and inorganic phosphate.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.