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Ganciclovir

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Ganciclovir

Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.

Ganciclovir was patented in 1980 and approved for medical use in 1988.

Ganciclovir is indicated for:

It is also used for acute CMV colitis in HIV/AIDS and CMV pneumonitis in immunosuppressed patients.[medical citation needed]

Ganciclovir has also been used with some success in treating Human herpesvirus 6 infections.

Ganciclovir has also been found to be an effective treatment for herpes simplex virus epithelial keratitis.

Ganciclovir (in gel form) appears to be effective for treating the ophthalmic Felid herpesvirus 1 (FHV-1) virus infection in cats.

Ganciclovir is commonly associated with a range of serious haematological adverse effects. Common adverse drug reactions (≥1% of patients) include: granulocytopenia, neutropenia, anaemia, thrombocytopenia, fever, nausea, vomiting, dyspepsia, diarrhea, abdominal pain, flatulence, anorexia, raised liver enzymes, headache, confusion, hallucination, seizures, pain and phlebitis at injection site (due to high pH), sweating, rash, itch, increased serum creatinine and blood urea concentrations.

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