Genoa was an Italian restaurant in Portland, Oregon, in the United States. Housed in the Genoa Building, the restaurant closed permanently in 2014. Laurie Wolf said Genoa "was at the forefront of Portland's changing food scene".

Genoa was an Italian restaurant housed on Belmont Street in the Genoa Building, in southeast Portland's Sunnyside neighborhood. Fodor's said, "The dining room's dark antique furnishings, long curtains, and dangling light fixtures lend it an air of sophistication, and with seating limited to under a few dozen diners, service is excellent."

In 2010, Patrick Alan Coleman of the Portland Mercury said of Genoa: "The restaurant has a feeling of cloistered austerity, shielded as it is from the street with heavy curtains. Inside, the dining room is all dark tones with an almost mortuary-like solemnity, save for the inoffensive selection of quiet modern music and chandeliers that break up the brown walls with nifty geometric shadows."

Genoa's menu changed seasonally. The restaurant served appetizers, salads, pastas, and desserts. The menu included duck breast with onions, apples, and arugula, as well as steelhead trout with brioche, caramelized yogurt, and butternut squash. Genoa also served foie gras.

The duck egg, served sous vide, was described by The Oregonian as "a setting sun of orange yolk pudding amid a landscape of pimenton-dyed croutons and asparagus shaved white up to their spear tips". The newspaper said, "Thin, rare-pink slices of 'corned' lamb were woven around dry chickpeas, hummus and dots of bright-green nasturtium leaf pesto." Genoa's version of strawberries and cream had berries "[alternating] with velvety tarragon-infused fromage blanc, all scattered with orange and purple nasturtium petals".

Local restaurateur Michael Vidor opened Genoa in 1971. In an interview with The Oregonian, he said the restaurant's northern Italian cuisine "is nothing more than a dinner party you would have at home... one you gave a lot of thought to".

Former owners include Amelia Hard and Kerry DeBuse. Chef/owner Cathy Whims, who started at the restaurant as a dishwasher, left in 2002. Robert Reynolds was briefly a consulting executive chef in 2005. John Taboada, the chef-owner of Navarre, was a cook at Genoa.

Genoa closed in 2007 or 2008, and was rebooted in 2009, with David Anderson as executive chef. According to The Oregonian, "Once onboard, Anderson immersed himself in all things Genoa, visiting Italy for two weeks, poring over books of Genoa recipes and menus, and chatting with such kitchen alums as Nostrana chef Cathy Whims. The familiar 50-seat space was stripped to its skeleton, then rebuilt to resemble the original. New features are the dark blue and gold silk drapery, a fireplace in the main dining room and five stunning stained-glass chandeliers resembling wind chimes."