GenomeWeb LLC is an online news organization based in New York City, New York. Established in 1997, it aims to report scientific and business news related to genomics.

GenomeWeb LLC was founded in 1997 by publishing entrepreneur Dennis Waters. It initially published only two newsletters: BioInform and Agricultural Genomics. Soon afterward, the company launched several more newsletters, as well as a magazine and a set of blogs on their website. By 2011, the company published eight newsletters, a news website, and the print magazine Genome Technology. In September 2019, it was acquired by Crain Communications.