Gianluca Scamacca (born 1 January 1999) is an Italian professional footballer who plays as a striker for Serie A club Atalanta and the Italy national team.

Scamacca previously played for Jong PSV, Sassuolo and West Ham United, with loans at Cremonese, PEC Zwolle, Ascoli and Genoa. He made his senior international debut for Italy in 2021.

A product of the youth academies of Lazio and Roma, Scamacca joined PSV Eindhoven in January 2015. He made his professional debut in Eerste Divisie as a Jong PSV player on 22 January 2016, aged 17, in a 2–1 away win against VVV-Venlo, replacing Steven Bergwijn after 61 minutes.

In January 2017, he was signed by Italian club Sassuolo on a four-and-a-half-year deal. On 29 October, at age 18, he made his Serie A debut in a 3–1 loss against Napoli at the Stadio San Paolo, coming on as a substitute for Diego Falcinelli in the 85th minute.

In January 2018, Scamacca joined Serie B club Cremonese on loan. He scored his first professional goal on 14 April 2018, in the league match against Palermo.

On 31 August 2018, Scamacca joined Eredivisie club PEC Zwolle on loan. He made his debut on 2 September 2018 in the away league match won 1–0 against Groningen.

On 13 July 2019, he joined Serie B club Ascoli on loan.

On 2 October 2020, Scamacca joined Genoa in the Serie A on a season-long loan.