Glenville High School is a public high school in Glenville neighborhood of Cleveland, Ohio and part of the Cleveland Metropolitan School District. Athletic teams are known as the Tarblooders and the compete in the Ohio High School Athletic Association as a member of the Senate Athletic League.

Glenville's first high school was opened in 1892 on Parkwood Drive. Rapid enrollment growth led to the opening of a new high school, later built in 1904. The village of Glenville was annexed by Cleveland in 1906, making the high school a part of the Cleveland public school system. During the early 20th century Glenville High School reflected the changing character of its surrounding neighborhood. As Jewish families moved from Cleveland’s Woodland area into Glenville, the school’s student body became predominantly Jewish, reportedly reaching about 90 percent at one point. In the decades after World War II, demographic changes in the neighborhood transformed the school again, and Glenville became an important center of African American education and community life on Cleveland’s East Side.

Because of continued growth, the original Parkwood building eventually became overcrowded despite several additions. Funding for a replacement facility was approved in the early 1960s, and a new Glenville High School building opened in 1966 at 650 East 113th Street. The newer campus included updated academic spaces, science facilities, and a large gymnasium built to serve the school’s sizable student population.