Great Lever (/ˈleɪvə(r)/, LAY-ver) is a suburb of Bolton, Greater Manchester, England. Historically in Lancashire, it is 2+1⁄2 miles (4.0 km) south of Bolton town centre and the same distance north of Farnworth. The district is served by frequent buses running to Bolton town centre, Farnworth and the Royal Bolton Hospital. The population is 16,969.

The parish church of St. Michael (with St Bartholomew) is a Grade II listed building.

On Green Lane there is one large public house: Southfield's, a pub and restaurant and The Brooklyn (now a private school). Both were houses built for local mill owners.

Beehive Mill (now demolished) on Crescent Road.

On the opposite side of Green Lane from the park are the grounds of Bolton Cricket Club. The two conjoined Doe Hey Reservoirs are used for private fishing. Will Hill Brook, which drains into the Doe Hey Reservoirs, forms the southern boundary between Great Lever and Farnworth.

Primary schools in Great Lever include Bishop Bridgeman CE Primary School, Essa Primary School, Lever Edge Primary Academy, St Michael's CE Primary School, SS Simon and Jude CE Primary School and St William of York RC Primary School. There are also numerous play-centres for pre-school children.

The former public house, The Brooklyn is now the independent school Lord's College.

The main secondary school in the area is Essa Academy for pupils aged 11 to 16.