Grindleford railway station serves the village of Grindleford in the Derbyshire Peak District, England. It is located 1 mile (1.6 km) away from the village centre in Nether Padley. The station is a stop on the Hope Valley Line between Manchester Piccadilly and Sheffield.

It was opened in 1894 on the Midland Railway's Dore and Chinley line (now the Hope Valley Line), at the western entrance to the Totley Tunnel.

The line opened up the previously isolated valley to day-trippers to Padley Gorge and commuters from Sheffield, and the transport of stone from the local quarries. The station buildings are still standing and now house a well-known café.

The station is unstaffed and had no ticket provision until 2018; however, Northern has now installed ticket vending machines and made the intermediate stations between New Mills Central and Sheffield part of a penalty fare scheme.

Standard waiting shelters are provided on both platforms and train running information is offered via CIS displays, automated announcements, a pay phone and timetable posters. Step-free access is available for westbound trains only (platform 1), as the ramps to the bridge linking the platforms are steep and not suitable for wheelchairs.

The typical off-peak service from the station is one train per hour in each direction between Sheffield and Manchester Piccadilly.

On Sundays, services begin mid-morning and continue at hourly intervals during the day.

Trains to Sheffield take around 15 minutes; the journey to Manchester Piccadilly takes about an hour. Services are provided by Northern Trains.