HP Inc. targets their line of business desktop computers for use in the corporate, government, and education markets. HP operate their business desktops on minimum 12-month product cycle. Their product line mainly competes with Dell OptiPlex, Acer Veriton, and Lenovo ThinkCentre.

HP's market share for their business line of desktops in 2010 was estimated to be 18.7 percent in 2022.

HP's business desktops are available as number of brand names including HP Business, HP Pro, HP Elite.

HP's entry-level business desktops typically include 2 memory slots, as opposed to 4 in the higher-tier ranges, thus limiting the maximum amount of RAM that can be installed. Units typically use lower-tier motherboards with cheaper and less-feature-rich chipsets.

In tables below, the Chassis column occasionally uses prefixal:
C = Convertible... and
US = Ultra-slim...
along with the following acronyms:
AIO = All-in-One
DM = Desktop Mini
DT = Desktop
MT = Minitower
SFF = Small Form Factor
ST = Slim Tower
TWR = Tower

TWR - Tower
(C)MT - (Convertible) Minitower
ST - Slim Tower
SFF - Small Form Factor
US(DT) - Ultra-slim (Desktop)
DM - Desktop Mini
AIO - All-in-One