Kojima cites a wide range of films and books as key influences, including science fiction works by Arthur C. Clarke, Stanley Kubrick's films, and the works of directors like David Lynch. He is drawn to stories with complex themes and philosophical undertones.

Music plays an integral part in Kojima's creative process. He's known to carefully select soundtracks that enhance the atmosphere and emotional impact of his games. He collaborates with renowned composers such as Harry Gregson-Williams and Ludvig Forssell.

Kojima's games often incorporate political and social commentary, exploring themes such as war, nuclear disarmament, genetic engineering, and the nature of society. He uses his games as a platform to reflect on real-world issues.

The Cold War era and espionage films heavily influenced the Metal Gear series, particularly the early installments. The themes of political intrigue, nuclear threat, and moral ambiguity are central to the series' narrative.

Death Stranding is influenced by existentialist philosophy and the concept of human connection in a fragmented world. Kojima explores themes of loneliness, isolation, and the importance of rebuilding societal bonds.