High Bridge is a historic former railroad bridge across the Appomattox River valley about 6 miles (9.7 km) east, or downstream, of the town of Farmville in Prince Edward County, Virginia. The remains of the bridge and its adjacent rail line are now a rail trail park, High Bridge Trail State Park.

Originally constructed in the 1850s, the bridge was integral to the Southside Railroad between Petersburg and Lynchburg. As the site of the Battle of High Bridge in April 1865, the bridge played a pivotal role in Lee's retreat in the final days of the American Civil War – and ultimately the war's outcome. Rebuilt after the Civil War to its former dimensions, the 21-span structure was 2,400 feet (730 m) long at a maximum height of 125 feet (38 m) above the Appomattox River Valley. The bridge was completely rebuilt in 1914, leaving many of the original masonry piers adjacent to the new structure.

By 2005 its then-owner, Norfolk Southern, abandoned the corridor, subsequently giving 33 miles of the line to the Virginia Department of Conservation and Recreation (DCR). High Bridge opened to the public on April 6, 2012, the 147th anniversary of the Battle of High Bridge. The bridge is part of the completed trail, open to hiking, biking and horse back riding for 16 miles on either side of the bridge.

In the 1850s, the Southside Railroad built a rail line between Petersburg and Lynchburg, passing through Farmville between Burkeville and Pamplin City. The route, subsidized by a contribution from Farmville, required an expensive crossing of the Appomattox River valley, at a site near property known as Overton farm.

The site was surveyed and the bridge engineered by C.O. Sanford, who later reported to the stockholders of the Southside Railroad: "there have been higher bridges not so long, and longer bridges not so high, but taking the length and height together, this is, perhaps the largest bridge in the world."

The High Bridge's twenty piers contained almost four million bricks, and supported a wooden superstructure with a pedestrian walkway beside the rail line – along with an adjacent wagon bridge (known also as the lower wagon bridge) — which would ultimately play a pivotal role in the outcome of the Civil War. The bridge itself was completed in 1852 and the full line was completed in 1854.

The Southside Railroad was heavily damaged during the American Civil War. The High Bridge played a key role during Confederate General Robert E. Lee's final retreat from Petersburg in the last days of the War. The Battle of High Bridge took place there on April 6–7, 1865. Fleeing the Union troops, the Confederates set the bridge afire after crossing it, but failed to destroy it. Union troops were able to use it and continued the chase, which ended several days later at Appomattox Courthouse, where Lee's surrender to Union General Ulysses S. Grant took place on April 9, 1865.

After the Civil War, Robert E. Lee directed the Confederate engineers who had attempted to destroy the bridge to rebuild it. Under the leadership of former Confederate General William "Billy" Mahone, the bridge was rebuilt, including 21 new Fink deck truss spans on the High Bridge erected in 1869.