.jpg/250px-Histoplasma_capsulatum_(8538519681).jpg){kind=small}
.jpg)
Community hub
Recent from talks
Contribute something
Nothing was collected or created yet.
Histoplasma
View on Wikipedia
| Histoplasma | |
|---|---|
.jpg)
| |
| Tuberculate macroconidia of Histoplasma capsulatum | |
Scientific classification 
| |
| Kingdom: | Fungi |
| Division: | Ascomycota |
| Class: | Eurotiomycetes |
| Order: | Onygenales |
| Family: | Ajellomycetaceae |
| Genus: | Histoplasma Darling (1906) |
| Type species | |
| Histoplasma capsulatum Darling (1906)
| |
| Species | |
|
Histoplasma capsulatum | |
Histoplasma is a genus of fungi in the order Onygenales.[1] Species are known human pathogens producing yeast-like states under pathogenic conditions. They are the causative agents of histoplasmosis in humans and epizootic lymphangitis in horses.[2]
Forms and stages
[edit]Histoplasma species have two forms: their environmental form is hyphal with microconidia and tuberculate macroconidia while their pathogenic form is a small intracellular yeast that exhibits narrow-necked budding[3] and no capsule.[4][5] Infection occurs through inhalation of microconidia or small mycelial fragments. The dimorphic mold-yeast transforms and enters host macrophages and proliferates within them. Infections are most often seen in immunodeficient individuals.[6]
Species are mainly found in the Ohio and Mississippi River Valleys in the United States (H.ohiense and H. mississippiense) as well as Central (H. capsulatum) and South America (H. suramericanum), Africa (H. duboisii), Asia, and Australia.[7][8]
References
[edit]- ^ Jiang Y, Dukik K, Munoz JF, Sigler L, Schwartz IS, Govender NP, Kenyon C, Feng P, van den Ende BG, Stielow JB, Stchigel AM, Lu H, de Hoog S (2018). "Phylogeny, ecology and taxonomy of systemic pathogens and their relatives in Ajellomycetaceae (Onygenales): Blastomyces, Emergomyces, Emmonsia, Emmonsiellopsis". Fungal Diversity. 90: 245–291. doi:10.1007/s13225-018-0403-y. hdl:10067/1520590151162165141.
- ^ OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2.5.13, "Archived copy". Archived from the original on 2007-08-04. Retrieved 2007-06-14.
{{cite web}}: CS1 maint: archived copy as title (link) - ^ Mittal, Jamie; Ponce, Maria G.; Gendlina, Inessa; Nosanchuk, Joshua D. (2019). "Histoplasma Capsulatum: Mechanisms for Pathogenesis". In Rodrigues, Marcio L. (ed.). Fungal Physiology and Immunopathogenesis. Current Topics in Microbiology and Immunology volume 422. Vol. 422. Springer Nature Switzerland AG. pp. 157–191. doi:10.1007/82_2018_114. ISBN 978-3-030-30236-8. PMC 7212190. PMID 30043340.
- ^ Mahajan, Monika (2021). "Etymologia: Histoplasma capsulatum". Emerging Infectious Diseases. 27 (3): 969. doi:10.3201/eid2703.et2703. PMC 7920646.
- ^ Hutton, JP (April 1985). "Hyphal forms of Histoplasma capsulatum. A common manifestation of intravascular infections". Archives of Pathology and Laboratory Medicine. 109 (4): 330–332. PMID 3885898.
- ^ Lopez, CE (Oct 2006). "Dimorphism and pathogenesis of Histoplasma capsulatum". Revista Argentina de Microbiologia. 38 (4): 235–242. PMID 17370580.
- ^ "Histoplasmosis". Centers for Disease Control and Prevention. 28 October 2020. Retrieved 27 January 2021.
- ^ Sepúlveda VE, Márquez R, Turissini DA, Goldman WE, Matute DR (2017). "Genome sequences reveal cryptic speciation in the human pathogen Histoplasma capsulatum". mBio. 8 (6): e01339-17. doi:10.1128/mbio.01339-17. PMC 5717386. PMID 29208741.
 | This Eurotiomycetes-related article is a stub. You can help Wikipedia by expanding it. |